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Heartburn, also known as pyrosis, cardialgia or acid indigestion, [2] is a burning sensation in the central chest or upper central abdomen. [3][4][5] Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus. It is the major symptom of gastroesophageal reflux disease (GERD). [6]
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. [6][7][10] Symptoms include dental corrosion, dysphagia, heartburn, odynophagia, regurgitation ...
Frequency. ~25% of babies [1] Baby colic, also known as infantile colic, is defined as episodes of crying for more than three hours a day, for more than three days a week, for three weeks in an otherwise healthy child. [1] Often crying occurs in the evening. [1] It typically does not result in long-term problems. [4]
For GERD, though, the sunny fruits can spell trouble. They're highly acidic, prompting the stomach to create excess acid. Try removing lemons, limes, oranges, and grapefruit during a reflux flare ...
Campylobacter pylori Marshall et al. 1985. Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape that exhibits less virulence. [1][2] Its helical body (from which the genus name Helicobacter derives) is thought to have evolved to penetrate ...
Additionally an operation known as a Nissen fundoplication can reduce the reflux of acid from the stomach into the esophagus. [40] In a variety of studies, nonsteroidal anti-inflammatory drugs such as low-dose aspirin (75–300 mg/day) have shown evidence of preventing esophageal cancer in people with Barrett's esophagus. [41] [42] [43] [44]
Acid peptic diseases, such as peptic ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease, are caused by distinct but overlapping pathogenic mechanisms involving acid effects on mucosal defense. Acid reflux damages the esophageal mucosa and may also cause laryngeal tissue injury, leading to the development of pulmonary symptoms.
Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or the nasopharynx. [4] [5] LPR causes respiratory symptoms such as cough and wheezing [6] and is often associated with head and neck complaints such as dysphonia, globus pharyngis, and dysphagia. [7]
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