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Metformin itself isn’t thought to cause hair loss, but type 2 diabetes and PCOS (polycystic ovary syndrome) — the conditions it’s prescribed to treat — can cause hair loss.
1. Diet. Being in a calorie surplus — consuming more calories than you burn — can lead to overall weight gain and increase your chances of developing belly fat.
Metformin can help you lose weight and reduce your BMI and waist circumference. And alongside weight loss, it can cut your risk of type 2 diabetes if you’re at high risk for the condition.
Amylin analogues can both reduce energy intake and increase expenditure and can usefully be combined with leptin analogues for synergistic effect. [25] [26] The dual amylin and calcitonin receptor agonist cagrilintide, in combination with semaglutide, was more effective than semaglutide alone in promoting weight loss in clinical trials. [27] [28]
Vildagliptin/metformin is indicated in the treatment of type-2 diabetes mellitus: [4] [6] [7] it is indicated in the treatment of adults who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone or who are already treated with the combination of vildagliptin and metformin as separate tablets.
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia. This can be a medication or a naturally occurring neuropeptide hormone, such as ghrelin , orexin or neuropeptide Y , [ 1 ] [ 2 ] which increases hunger and therefore enhances food consumption .
In addition to metformin, the kit contains addiction medications (to “reduce cravings and appetite”), a seizure medication that suppresses appetite and vitamin B12 (“for balance”).
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