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On 10 June 2014, the United Kingdom's Home Office classified tramadol as a Class C, Schedule 3 controlled drug, but exempted it from the safe custody requirement. [ 133 ] On 1 October 2023, New Zealand's Medsafe reclassified tramadol as a Class C2 Controlled Drug (in addition to its existing status as a prescription only medication).
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
Effexor and Effexor XR (venlafaxine) – an antidepressant of the SNRI class Elavil ( amitriptyline ) – a tricyclic antidepressant used as a first-line treatment for neuropathic pain Eurodin , Prosom ( estazolam ) – a benzodiazepine derivative with anxiolytic , anticonvulsant , hypnotic , sedative and skeletal muscle relaxant properties ...
PHOTO: Semaglutide (GLP-1) weight-loss drug Wegovy, made by pharmaceutical company Novo Nordisk is seen on Oct. 16, 2024. (James Manning/PA Images via Getty Images)
There are positives to this effect—namely weight loss, but also potentially treating substance use and addiction, likely due to GLP-1s’ effect on the hypothalamus.
Patients with obesity can now also take Zepbound, a rival weight-loss drug made by Eli Lilly. It was approved by the FDA in 2023 and contains a different active ingredient.
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [ 6 ] [ 9 ] It is used to treat major depressive disorder , generalized anxiety disorder , panic disorder , and social anxiety disorder . [ 9 ]
Weight gain. In general, large-scale studies do tend to show that long-term use of antidepressants is associated with weight gain side effects. However, study data on escitalopram and weight ...
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