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  2. Single-nucleotide polymorphism - Wikipedia

    en.wikipedia.org/wiki/Single-nucleotide_polymorphism

    In genetics and bioinformatics, a single-nucleotide polymorphism (SNP / s n ɪ p /; plural SNPs / s n ɪ p s /) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), [ 1 ...

  3. SNP genotyping - Wikipedia

    en.wikipedia.org/wiki/SNP_genotyping

    SNPs are one of the most common types of genetic variation. An SNP is a single base pair mutation at a specific locus, usually consisting of two alleles (where the rare allele frequency is > 1%). SNPs are found to be involved in the etiology of many human diseases and are becoming of particular interest in pharmacogenetics.

  4. Tufts University Graduate School of Biomedical Sciences

    en.wikipedia.org/wiki/Tufts_University_Graduate...

    The Tufts University School of Medicine (TUSM) and the Graduate School of Biomedical Sciences (GSBS) are located in five adjoining research buildings along Boston's Harrison Avenue and a teaching and administrative building, the Tufts Center for Medical Education (formerly the Arthur M. Sackler Center for Medical Education). The newest addition ...

  5. Genealogical DNA test - Wikipedia

    en.wikipedia.org/wiki/Genealogical_DNA_test

    A person's haplogroup can often be inferred from their STR results, but can be proven only with a Y-chromosome SNP test (Y-SNP test). A single-nucleotide polymorphism (SNP) is a change to a single nucleotide in a DNA sequence. Typical Y-DNA SNP tests test about 20,000 to 35,000 SNPs. [34] Getting a SNP test allows a much higher resolution than ...

  6. SNP array - Wikipedia

    en.wikipedia.org/wiki/SNP_array

    In molecular biology, SNP array is a type of DNA microarray which is used to detect polymorphisms within a population. A single nucleotide polymorphism (SNP), a variation at a single site in DNA , is the most frequent type of variation in the genome.

  7. Kompetitive allele specific PCR - Wikipedia

    en.wikipedia.org/wiki/Kompetitive_allele...

    A single-nucleotide polymorphism (SNP) occurs when a single nucleotide in a DNA sequence differs between members of the same species or a paired chromosome. SNPs work as molecular markers that help locate genes associated with disease and are used for genotype sequencing.

  8. Allele frequency spectrum - Wikipedia

    en.wikipedia.org/wiki/Allele_frequency_spectrum

    The allele frequency spectrum can be written as the vector = (,,,,), where is the number of observed sites with derived allele frequency .In this example, the observed allele frequency spectrum is (,,,,), due to four instances of a single observed derived allele at a particular SNP loci, two instances of two derived alleles, and so on.

  9. Genotyping by sequencing - Wikipedia

    en.wikipedia.org/wiki/Genotyping_by_sequencing

    In the field of genetic sequencing, genotyping by sequencing, also called GBS, is a method to discover single nucleotide polymorphisms (SNP) in order to perform genotyping studies, such as genome-wide association studies . [1] GBS uses restriction enzymes to reduce genome complexity and genotype multiple DNA samples. [2]