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Jewish populations, and particularly the large Ashkenazi Jewish population, are ideal for such research studies, because they exhibit a high degree of endogamy, and at the same time are a large group. Jewish populations are overwhelmingly urban and are concentrated near biomedical centers where such research has been carried out.
Ashkenazi Jews have a high incidence of Tay–Sachs and other lipid storage diseases. In the United States, about 1 in 27 to 1 in 30 Ashkenazi Jews is a recessive carrier. The disease incidence is about 1 in every 3,500 newborns among Ashkenazi Jews. [40] French Canadians and the Cajun community of Louisiana have an occurrence similar to the ...
However, the disorder is relatively more common amongst people of Central and Eastern European Ashkenazi Jewish background. Approximately 1 in 48,000 Ashkenazi Jews are affected by Bloom syndrome, who account for about one-third of affected individuals worldwide.
It tends to run in Ashkenazi Jewish families like mine (it typically occurs in about 1 in 50,000 people, but occurs in nearly 1 in 500 people with Ashkenazi Jewish heritage). The doctor had ...
A 2009 study by Goldstein et al. shows that it is possible to predict full Ashkenazi Jewish ancestry with 100% sensitivity and 100% specificity, although the exact dividing line between a Jewish and non-Jewish cluster will vary across sample sets which in practice would reduce the accuracy of the prediction.
Hackers have compiled a giant apparent list of people with Ashkenazi Jewish ancestry after taking that information from the genetic testing service 23andMe, which is now being shared on the internet.
The Program for Jewish Genetic Health offers educational programs – both live and online – to various sectors of the community to educate them on Jewish genetic health issues, including the Ashkenazi Jewish link to breast and ovarian cancer, Parkinson's disease, and prostate cancer, as well as alternative family planning options such as pre-implantation genetic diagnosis.
When my Ashkenazi Jewish family immigrated to the US from Poland and Ukraine at the start of the 20th century, they and others like them were labeled by American society as “aliens” and “a ...