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  2. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Some MS patients develop rapid onset of numbness, weakness, bowel or bladder dysfunction, and/or loss of muscle function, typically in the lower half of the body. [citation needed] This is the result of MS attacking the spinal cord. The symptoms and signs depend upon the nerve cords involved and the extent of the involvement.

  3. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease, MS disrupts the nervous system's ability to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.

  4. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    Multiple sclerosis is typically diagnosed based on the presenting signs and symptoms, in combination with supporting medical imaging and laboratory testing. [4] It can be difficult to confirm, especially early on, since the signs and symptoms may be similar to those of other medical problems. [5] [6]

  5. Management of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_multiple...

    For other symptoms the efficacy of treatments is still very limited. [87] Aquatic therapy has also been shown to alleviate symptoms of multiple sclerosis. Aquatic cycling and aerobic exercise is a safe and effective way to increase muscular strength, endurance, and circulation in MS patients.

  6. Uhthoff's phenomenon - Wikipedia

    en.wikipedia.org/wiki/Uhthoff's_phenomenon

    Uhthoff's phenomenon (also known as Uhthoff's syndrome, [1] Uhthoff's sign, [1] and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated.

  7. Diffuse myelinoclastic sclerosis - Wikipedia

    en.wikipedia.org/wiki/Diffuse_myelinoclastic...

    Symptoms and signs [ edit ] Symptoms are similar to those in multiple sclerosis and may include dementia , aphasia , seizures , personality changes , poor attention , tremors , balance instability , incontinence, muscle weakness, headache, vomiting, and vision and speech impairment. [ 5 ]

  8. Radiologically isolated syndrome - Wikipedia

    en.wikipedia.org/wiki/Radiologically_isolated...

    Currently, routine clinical follow-up and MRI neuroimaging surveillance is the standard by which patients are observed. [4] While treatment of MS disease modifying therapies have been given to some individuals with RIS, the majority opt for active surveillance and the appearance of clinical symptoms before commencing treatment, [5] as treatment is considered controversial.

  9. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    A rarer type of classical ALS affecting around 3% of patients is respiratory-onset, [9] in which the initial symptoms are difficulty breathing upon exertion, at rest, or while lying flat . [ 25 ] Primary lateral sclerosis (PLS) is a subtype of the overall ALS category which accounts for about 5% of all cases and only affects the upper motor ...

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