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  2. Baclofen - Wikipedia

    en.wikipedia.org/wiki/Baclofen

    Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  4. Informant Questionnaire on Cognitive Decline in the Elderly

    en.wikipedia.org/wiki/Informant_Questionnaire_on...

    The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) is a questionnaire that can be filled out by a relative or other supporter of an older person to determine whether that person has declined in cognitive functioning. The IQCODE is used as a screening test for dementia. If the person is found to have significant cognitive ...

  5. Memory and aging - Wikipedia

    en.wikipedia.org/wiki/Memory_and_aging

    A biological explanation for memory deficits in aging includes a postmortem examination of five brains of elderly people with better memory than average. These people are called the "super aged," and it was found that these individuals had fewer fiber-like tangles of tau protein than in typical elderly brains.

  6. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's_disease

    It most often begins in people over 65 years of age, although up to 10% of cases are early-onset impacting those in their 30s to mid-60s. [27] [4] It affects about 6% of people 65 years and older, [16] and women more often than men. [28] The disease is named after German psychiatrist and pathologist Alois Alzheimer, who first described it in ...

  7. Dementia with Lewy bodies - Wikipedia

    en.wikipedia.org/wiki/Dementia_with_Lewy_bodies

    People with Lewy body dementias who take neuroleptics are at risk for neuroleptic malignant syndrome, a life-threatening illness. [51] There is no evidence to support the use of antipsychotics to treat the Lewy body dementias, [10] and they carry the additional risk of stroke when used in the elderly with dementia. [86]

  8. Prevention of dementia - Wikipedia

    en.wikipedia.org/wiki/Prevention_of_dementia

    The prevention of dementia involves reducing the number of risk factors for the development of dementia, and is a global health priority needing a global response. [1] [2] Initiatives include the establishment of the International Research Network on Dementia Prevention (IRNDP) [3] which aims to link researchers in this field globally, and the establishment of the Global Dementia Observatory ...

  9. Early-onset Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Early-onset_Alzheimer's...

    With some jobs, a mistake may have devastating consequences on a large number of people, and cases have been reported in which a person with early-onset Alzheimer's who is unaware of their condition has caused distress. [39] Younger people with Alzheimer's may also lose their ability to take care of their own needs, such as money management. [40]

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