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A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. [ 1 ] [ 2 ] A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency . [ 3 ]
Goiter is the general enlargement of the thyroid that can be associated with many thyroid diseases. The main reason this happens is because of increased signaling to the thyroid by way of TSH receptors to try to make it produce more thyroid hormone. [9] This causes increased vascularity and increase in size (hypertrophy) of the gland. [9]
Iodine deficiency causes gradual enlargement of the thyroid gland, referred to as a goiter. Poor length growth is apparent as early as the first year of life. Adult stature without treatment ranges from 100 to 160 cm (3 ft 3 in to 5 ft 3 in), depending on severity, sex, and other genetic factors.
Graves' disease, also known as toxic diffuse goiter or Basedow’s disease, is an autoimmune disease that affects the thyroid. [1] It frequently results in and is the most common cause of hyperthyroidism. [5] It also often results in an enlarged thyroid. [1]
Before 1950 goiter was a widespread disease caused by iodine deficiency. [40] Up to 80 percent of the population were affected in inland areas. In the coastal communities, saltwater fish were an important part of the diet, and because of the presence of iodine in seawater, goiter was less common than in the inland districts.
Iodine deficiency is the most common cause of primary hypothyroidism and endemic goiter worldwide. [8] [9] In areas of the world with sufficient dietary iodine, hypothyroidism is most commonly caused by the autoimmune disease Hashimoto's thyroiditis (chronic autoimmune thyroiditis). [8] [9] Hashimoto's may be
These can either generate gas or cause you to swallow more air, causing bloating. The Bottom Line If your belly feels like a balloon of air that won’t deflate, don’t despair.
2 Cause. 3 Diagnosis. Toggle Diagnosis subsection. 3.1 Types. 4 Treatment. ... Dyshormogenetic goiter: Thyroid dyshormonogenesis is inherited in an autosomal ...