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The term Cox regression model (omitting proportional hazards) is sometimes used to describe the extension of the Cox model to include time-dependent factors. However, this usage is potentially ambiguous since the Cox proportional hazards model can itself be described as a regression model.
The Cox PH regression model is a linear model. It is similar to linear regression and logistic regression. Specifically, these methods assume that a single line, curve, plane, or surface is sufficient to separate groups (alive, dead) or to estimate a quantitative response (survival time).
Sir David Roxbee Cox FRS FBA FRSE FRSC (15 July 1924 – 18 January 2022) was a British statistician and educator. His wide-ranging contributions to the field of statistics included introducing logistic regression, the proportional hazards model and the Cox process, a point process named after him.
Extensions of the Cox proportional hazard models are popular models in social sciences and medical science to assess associations between variables and risk of recurrence, or to predict recurrent event outcomes. Many extensions of survival models based on the Cox proportional hazards approach have been proposed to handle recurrent event data.
For instance, the from the Cox-model or the log-rank test might then be used to assess the significance of any differences observed in these survival curves. [ 9 ] Conventionally, probabilities lower than 0.05 are considered significant and researchers provide a 95% confidence interval for the hazard ratio, e.g. derived from the standard ...
The logrank test statistic compares estimates of the hazard functions of the two groups at each observed event time. It is constructed by computing the observed and expected number of events in one of the groups at each observed event time and then adding these to obtain an overall summary across all-time points where there is an event.
As compared to regression analysis, which creates a formula that health care providers can use to calculate the probability that a patient has a disease, recursive partition creates a rule such as 'If a patient has finding x, y, or z they probably have disease q'. A variation is 'Cox linear recursive partitioning'. [2]
A well-known example of a semiparametric model is the Cox proportional hazards model. [3] If we are interested in studying the time T {\displaystyle T} to an event such as death due to cancer or failure of a light bulb, the Cox model specifies the following distribution function for T {\displaystyle T} :