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WormBase is an online biological database about the biology and genome of the nematode model organism Caenorhabditis elegans and contains information about other related nematodes. [1] [2] WormBase is used by the C. elegans research community both as an information resource and as a place to publish and distribute their results. The database is ...
Capitalizing on the World Wide Web, WormBook links in-text references (e.g. genes, alleles, proteins, literature citations) with primary biological databases such as WormBase and PubMed. C. elegans was the first multicellular organism to have its genome sequenced [6] and is a model organism for studying developmental genetics and neurobiology.
C. elegans has been used in studies of development and neurobiology. WormBase has information from nine species and five are from the genus Caenorhabditis, one of which is C. elegans. WormBase provides: a genome browser, genome, gene and protein sets for searches on sequence similarities and gene and protein summaries. [3]
Caenorhabditis elegans (/ ˌ s iː n oʊ r æ b ˈ d aɪ t ə s ˈ ɛ l ə ɡ æ n s / [6]) is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. [7]
C. nigoni is the closest relative of C. briggsae, and the two species can occasionally produce somewhat fertile hybrids. [12] Caenorhabditis remanei - genome sequenced by WashU GSC. [13] More closely related to C. briggsae than C. elegans, C. remanei is a gonochoristic (male-female obligate) species in the Elegans group.
Caenorhabditis elegans: WormBase: WormBase [16] Rat Rattus norvegicus: Rat Genome Database: RGD [17] Social amoeba Dictyostelium discoideum: DictyBase: dictyBase [18] Ciliate Tetrahymena thermophila: Tetrahymena Genome Database: TGD: Thale cress Arabidopsis thaliana: The Arabidopsis Information Resource: TAIR [19] Maize Zea mays ssp. mays ...
C. elegans was first described in 1900 by Émile Maupas, who isolated it from soil in Algeria. [3] Ellsworth Dougherty proposed in 1948 that free-living nematodes of the sub-order Rhabditina might be useful for genetic study, noting their relative structural simplicity and invariant cell lineage (). [4]
UNC-129 is a ligand in the transforming growth factor family in C. elegans which encodes transforming growth factor β (TGF-β). Like UNC-6 it guides pioneer axons along the dorsoventral axis of C. elegans. TGF-β is expressed only in dorsal rows of body wall muscles and not ventral. [13]