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Acute kidney injury was one of the most expensive conditions seen in U.S. hospitals in 2011, with an aggregated cost of nearly $4.7 billion for approximately 498,000 hospital stays. [46] This was a 346% increase in hospitalizations from 1997, when there were 98,000 acute kidney injury stays. [47]
Kidney ischemia [1] is a disease with a high morbidity and mortality rate. [2] Blood vessels shrink and undergo apoptosis which results in poor blood flow in the kidneys. More complications happen when failure of the kidney functions result in toxicity in various parts of the body which may cause septic shock, hypovolemia, and a need for surgery. [3]
Wernicke encephalopathy ( WE ), also Wernicke's encephalopathy, [ 1] or wet brain is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B 1 ). [ 2] The condition is part of a larger group of thiamine deficiency disorders that ...
Glomerulonephrosis. Glomerulonephrosis is a non-inflammatory disease of the kidney ( nephrosis) presenting primarily in the glomerulus (a glomerulopathy) as nephrotic syndrome. The nephron is the functional unit of the kidney and it contains the glomerulus, which acts as a filter for blood to retain proteins and blood lipids.
Historically, nephritic syndrome has been characterized by blood in the urine ( hematuria ), high blood pressure ( hypertension ), decreased urine output <400 ml/day ( oliguria ), red blood cell casts, pyuria, and mild to moderate proteinuria. [ 8][ 9] If the condition is allowed to progress without treatment, it can eventually lead to azotemia ...
Rapidly progressive glomerulonephritis ( RPGN) is a syndrome of the kidney that is characterized by a rapid loss of kidney function, [ 4][ 5] (usually a 50% decline in the glomerular filtration rate (GFR) within 3 months) [ 5] with glomerular crescent formation seen in at least 50% [ 5] or 75% [ 4] of glomeruli seen on kidney biopsies.
Interstitial nephritis is uncommon (<1% incidence) in patients without any symptoms but occurs in about 10-15% of hospitalized patients with acute kidney injury of unknown cause. [2] While it can occur in patients of all ages, it is more common in elderly patients, perhaps due to increased exposure to drugs and other triggering causes. [2]
Cardiorenal syndrome. Cardiorenal syndrome (CRS) is an umbrella term used in the medical field that defines disorders of the heart and kidneys whereby "acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other". [ 1] When one of these organs fails, the other may subsequently fail. [ 2]
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