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Rare. Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people who take statin medications. [ 1] However, there are cases of SAAM in patients who have not taken statin medication, and this can be explained by the exposure to natural sources of ...
Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium) caused by ischemia, the lack of oxygen delivery to myocardial tissue. It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart.[22]
Coronary artery disease ( CAD ), also called coronary heart disease ( CHD ), ischemic heart disease ( IHD ), [ 13] myocardial ischemia, [ 14] or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [ 5][ 6][ 15] It is the most common of the ...
58260-1. Cardiac markers are biomarkers measured to evaluate heart function. They can be useful in the early prediction or diagnosis of disease. [ 1] Although they are often discussed in the context of myocardial infarction, other conditions can lead to an elevation in cardiac marker level. [ 2][ 3] Cardiac markers are used for the diagnosis ...
New research published in The Lancet says statins, the cholesterol-managing drug, do not cause muscle pain, despite them being commonly linked.
[5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34] This could be due to the statins inhibiting the enzyme (HMG-CoA reductase), which is necessary to make cholesterol, but also for other processes, such as CoQ 10 production, which ...
In studies using standard doses, statins have been found to lower LDL-C by 18% to 55%, depending on the specific statin being used. A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after ...
Simvastatin. Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [ 4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [ 4] It is also used to decrease the risk of heart problems in those at high risk. [ 4] It is taken by mouth.