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Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people who take statin medications. [ 1] However, there are cases of SAAM in patients who have not taken statin medication, and this can be explained by the exposure to natural sources of statin ...
Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium) caused by ischemia, the lack of oxygen delivery to myocardial tissue. It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart.[22]
Coronary artery disease ( CAD ), also called coronary heart disease ( CHD ), ischemic heart disease ( IHD ), [ 13] myocardial ischemia, [ 14] or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [ 5][ 6][ 15] It is the most common of the ...
Simvastatin. Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [ 4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [ 4] It is also used to decrease the risk of heart problems in those at high risk. [ 4] It is taken by mouth.
In studies using standard doses, statins have been found to lower LDL-C by 18% to 55%, depending on the specific statin being used. A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after ...
Lovastatin, a compound isolated from Aspergillus terreus, was the first statin to be marketed. Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease. They are the most commonly prescribed cholesterol-lowering drugs.
At autopsy, a pathologist can diagnose a myocardial infarction based on anatomopathological findings. A chest radiograph and routine blood tests may indicate complications or precipitating causes and are often performed upon arrival to an emergency department. New regional wall motion abnormalities on an echocardiogram are also suggestive of a ...
New research published in The Lancet says statins, the cholesterol-managing drug, do not cause muscle pain, despite them being commonly linked.