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The HuBMAP project has organized 1551 different samples in 17 collections, each dedicated to a different system. However, this project still only mapped about 31 of the human bodies' 70 organs. Their datasets and visualisations place great emphasis on biomarkers and location in the body, but less on cell development and how cells can change ...
The basement membrane, also known as base membrane, is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. [1] [2] The basement membrane sits between epithelial tissues including mesothelium and endothelium, and the underlying connective tissue. [3] [4]
There are four basic types of animal tissues: muscle tissue, nervous tissue, connective tissue, and epithelial tissue. [5] [9] All animal tissues are considered to be subtypes of these four principal tissue types (for example, blood is classified as connective tissue, since the blood cells are suspended in an extracellular matrix, the plasma). [9]
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. [1] It develops mostly from the mesenchyme , derived from the mesoderm , the middle embryonic germ layer . [ 2 ]
The mesothelium forms a monolayer of flattened squamous-like epithelial cells resting on a thin basement membrane supported by dense irregular connective tissue. Cuboidal mesothelial cells may be found at areas of injury, the milky spots of the omentum, and the peritoneal side of the diaphragm overlaying the lymphatic lacunae.
Epithelial cells can be squamous (flat), cuboidal or columnar and rest on a basal lamina, the upper layer of the basement membrane, [17] the lower layer is the reticular lamina lying next to the connective tissue in the extracellular matrix secreted by the epithelial cells. [18]
Functions of epithelial tissue: The principle function of epithelial tissues are covering and lining of free surface; The cells of the body's surface form the outer layer of skin. Inside the body, epithelial cells form the lining of the mouth and alimentary canal and protect these organs. Epithelial tissues help in the elimination of waste.
germinal epithelium (female) reproductive - female: fallopian tubes: Simple columnar, ciliated - reproductive - female: endometrium : Simple columnar, ciliated - reproductive - female: cervix : Simple columnar - reproductive - female: cervix : Stratified squamous, non-keratinized - reproductive - female: vaginal epithelium