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A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and gastrointestinal problems, among others.
GLP-1 medications are drugs that mimic the effects of the GLP-1 hormone, helping regulate blood sugar and reduce appetite. They are primarily used for managing type 2 diabetes but are also ...
GLP-1s quiet the urge to overeat and might also help you tackle issues like overdoing alcohol, smoking or vaping, and opioid overuse. “There is an overlap of brain circuitry used by appetite and ...
Native GLP-1 is a peptide hormone with a half-life of two minutes because it is rapidly cleared by the enzyme dipeptidyl peptidase-4. [29] As a result, different GLP-1 agonist drugs are modified in various ways to extend the half-life, resulting in drugs that can be dosed multiple times per day, daily, weekly, or less often. [29]
Taking a GLP-1 medication can come with both positive and negative side effects, but they can be more manageable with the right strategies. By focusing on a nutrient-rich diet, staying hydrated ...
Two popular drugs from a class called glucagon-like peptide receptor agonists or GLP-1s were approved in 2017 for treating type 2 diabetes. Three years ago, one was also approved for treating ...
The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage, which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
Even though GLP-1s and GIP/GLP-1s are safe for most people, there are some side effects to keep in mind. The most common side effects are gastrointestinal, particularly nausea and diarrhea. You ...