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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
Alendronic acid/colecalciferol, sold under the brand name Fosamax Plus D among others, is a medication for the treatment of osteoporosis in men or in postmenopausal women. [ 3 ] [ 2 ] [ 4 ] [ 6 ] Alendronic acid/colecalciferol was approved for use in the United States and in the European Union in 2005.
In osteoporosis and Paget's, the most popular first-line bisphosphonate drugs are alendronate and risedronate. If these are ineffective or if the person develops digestive tract problems, intravenous pamidronate may be used. Strontium ranelate or teriparatide are used for refractory disease.
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
Osteoporosis is defined as a bone density of 2.5 standard deviations below that of a young adult. ... alendronate was identified as ... The six-month mortality rate ...
English: *Drug Name: Alendronic acid 35 MG (as alendronate sodium 45.7 MG) Oral Tablet Ingredient(s): Alendronic acid Drug *Label Imprint: M;A11 Color(s): White
A dose of Eli Lilly's diabetes drug Mounjaro has limited availability through February 2024, according to the U.S. Food and Drug Administration's website, due to an increase in demand. The high ...
The likelihood of this condition developing varies widely from less than 1/10,000 to 1/100, as many other factors need to be considered, such as the type, dose and frequency of intake of drug, how long it has been taken for, and why it has been taken. [56] In patients taking drugs for cancer, the likelihood of MRONJ development varies from 0 - 12%.