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  2. Gene - Wikipedia

    en.wikipedia.org/wiki/Gene

    [1] [2] [3] During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA. RNA can be directly functional or be the intermediate template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next.

  3. Human genome - Wikipedia

    en.wikipedia.org/wiki/Human_genome

    HEXA gene (on chromosome 15) Canavan disease: 2.5% Eastern European Jewish ancestry ASPA gene (on chromosome 17) Familial dysautonomia: 600 known cases worldwide since discovery IKBKAP gene (on chromosome 9) Fragile X syndrome: 1.4:10000 in males, 0.9:10000 in females FMR1 gene (on X chromosome) Mucolipidosis type IV: 1:90 to 1:100 in Ashkenazi ...

  4. Nuclear organization - Wikipedia

    en.wikipedia.org/wiki/Nuclear_Organization

    For example, large, gene-poor chromosomes are commonly located on the periphery near the nuclear lamina while smaller, gene-rich chromosomes group closer to the center of the nucleus. [44] Second, individual chromosome preference is variable among different cell types. For example, the X-chromosome has shown to localize to the periphery more ...

  5. Chromosome - Wikipedia

    en.wikipedia.org/wiki/Chromosome

    This is an accepted version of this page This is the latest accepted revision, reviewed on 22 February 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...

  6. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    Data sets representing entire genomes' worth of DNA sequences, such as those produced by the Human Genome Project, are difficult to use without the annotations that identify the locations of genes and regulatory elements on each chromosome. Regions of DNA sequence that have the characteristic patterns associated with protein- or RNA-coding ...

  7. Chromatin - Wikipedia

    en.wikipedia.org/wiki/Chromatin

    The local structure of chromatin during interphase depends on the specific genes present in the DNA. Regions of DNA containing genes which are actively transcribed ("turned on") are less tightly compacted and closely associated with RNA polymerases in a structure known as euchromatin, while regions containing inactive genes ("turned off") are ...

  8. Cell nucleus - Wikipedia

    en.wikipedia.org/wiki/Cell_nucleus

    Gene expression first involves transcription, in which DNA is used as a template to produce RNA. In the case of genes encoding proteins, that RNA produced from this process is messenger RNA (mRNA), which then needs to be translated by ribosomes to form a protein. As ribosomes are located outside the nucleus, mRNA produced needs to be exported. [60]

  9. Genome - Wikipedia

    en.wikipedia.org/wiki/Genome

    The term "genome" usually refers to the DNA (or sometimes RNA) molecules that carry the genetic information in an organism, but sometimes it is uncertain which molecules to include; for example, bacteria usually have one or two large DNA molecules (chromosomes) that contain all of the essential genetic material but they also contain smaller ...