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  2. Epidermis - Wikipedia

    en.wikipedia.org/wiki/Epidermis

    The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.

  3. Stratum corneum - Wikipedia

    en.wikipedia.org/wiki/Stratum_corneum

    Sampling of human stratum corneum using a tape-stripping method [1] The stratum corneum (Latin for 'horned layer') is the outermost layer of the epidermis. Consisting of dead tissue, it protects underlying tissue from infection, dehydration, chemicals and mechanical stress. It is composed of 15–20 layers of flattened cells with no nuclei and ...

  4. Phenol-soluble modulin - Wikipedia

    en.wikipedia.org/wiki/Phenol-soluble_modulin

    PSMs were first described as a pro-inflammatory molecule. [2] This role has been repeatedly demonstrated to be true. PSMs are able to induce the production of a variety of cytokines as well as induce neutrophils to migrate to sites of infection. [3] PSMε in S. epidermidis is known to influence the production of IL-8. [3]

  5. Staphylococcus epidermidis - Wikipedia

    en.wikipedia.org/wiki/Staphylococcus_epidermidis

    Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. [1] It is part of the normal human microbiota, typically the skin microbiota, and less commonly the mucosal microbiota and also found in marine sponges.

  6. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.

  7. Skin flora - Wikipedia

    en.wikipedia.org/wiki/Skin_flora

    The project was designed with the aim of countering that misconception that bacteria are always harmful to humans [20] and that humans are at war with bacteria. [21] In actuality, most strains of bacteria are harmless [13] if not beneficial for the human body. [22] Another of the project's goals is to foster public interest in microbiology. [17]

  8. Involucrin - Wikipedia

    en.wikipedia.org/wiki/Involucrin

    Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. [7] [8] It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor ...

  9. Skin - Wikipedia

    en.wikipedia.org/wiki/Skin

    The word skin originally only referred to dressed and tanned animal hide and the usual word for human skin was hide. Skin is a borrowing from Old Norse skinn "animal hide, fur", ultimately from the Proto-Indo-European root *sek-, meaning "to cut" (probably a reference to the fact that in those times animal hide was commonly cut off to be used as garment).