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Thumb hypoplasia is a spectrum of congenital abnormalities of the thumb varying from small defects to complete absence of the thumb. [1] It can be isolated, when only the thumb is affected, and in 60% of the cases [ 2 ] it is associated with radial dysplasia [ 1 ] (or radial club, radius dysplasia, longitudinal radial deficiency).
Hypoplasia of the distal humerus may be present as well and can lead to stiffness of the elbow. [2] Radial deviation of the wrist is caused by lack of support to the carpus, radial deviation may be reinforced if forearm muscles are functioning poorly or have abnormal insertions. [ 3 ]
Although more research is needed, the genetic cause of radial hypoplasia is believed to come from a rare allele of the Sonic hedgehog (Shh) gene. [3] This gene produces the Shh protein that induces development of the ulna, and the index, middle, ring, and pinky fingers while increasing the expression of fibroblast growth factor (FGF), another signaling molecule, which induces development of ...
These are the best wrist braces for carpal tunnel, arthritis, sprains, pains and more. ... Dr. Frederick's original reversible copper-infused wrist and thumb brace offers comfortable, firm wrist ...
Trapeziometacarpal osteoarthritis (TMC OA) is, also known as osteoarthritis at the base of the thumb, thumb carpometacarpal osteoarthritis, basilar (or basal) joint arthritis, or as rhizarthrosis. [ 3 ] [ 1 ] [ 2 ] This joint is formed by the trapezium bone of the wrist and the metacarpal bone of the thumb.
In general the surgical treatment is done for improvement of the thumb function. However, an extra advantage of the surgery is the improvement in appearance of the thumb. In the past, surgical treatment of the triphalangeal thumb was not indicated, [11] but now it is generally agreed that operative treatment improves function and appearance ...
Ulnar dysplasia also known as ulnar longitudinal deficiency, ulnar club hand or ulnar aplasia/hypoplasia is a rare congenital malformation which consists of an underdeveloped or missing ulnae bone, causing an ulnar deviation of the entire wrist. The muscles and nerves in the hand may be missing or unbalanced.
Michels Caskey syndrome is a rare disorder that combines spinal and skeletal abnormalities, especially of the thumbs, with abnormal or absent female reproductive organs. . Examples include the absence of a cervix and upper vagina or abnormalities of the uterus or vag
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