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Insulin aspart can be used in an insulin pump and insulin pen for subcutaneous injection. Additionally, it can be used with an injection port such as the I-port. [25] Insulin aspart has a more rapid onset, and a shorter duration of activity than normal human insulin. [26] Insulin aspart can also be used with external insulin pumps. [13]
It is given as an injection under the skin in the abdominal wall (at the front of the waist), upper arm or thigh. [6] The most frequently reported side effect is hypoglycemia (low blood glucose levels). [6] It was approved for medical use in the European Union in January 2013, [6] and in Australia in November 2017. [2]
An injector pen consists of a chamber or cartridge of medication, a tip to attach a needle, and a piston or plunger to inject the dose. [4] Some pens, including most insulin pens, include dials to adjust the dose of the injection before each administration. [2]
Mylan Pharmaceuticals recalled one batch of Insulin Glargine Injection, 100 units/mL (U-100), 3 mL prefilled pens, which are sold in cartons of five. Some pens might be missing their labels.
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Insulin degludec is an ultra-long acting insulin that, unlike insulin glargine, is active at a physiologic pH.The addition of hexadecanedioic acid via an amide linkage to lysine at the B29 position allows for the formation of multi-hexamers in subcutaneous tissues. [16]
Another device used in intensive insulinotherapy is the injection port. An injection port is a small disposable device, similar to the infusion set used with an insulin pump, configured to accept a syringe. Standard insulin injections are administered through the injection port.
Insulin degludec is slightly different from human insulin as it is absorbed more slowly and regularly by the body after an injection and it works for a long time. [ 8 ] Liraglutide belongs to the class of diabetes medicines known as GLP-1 receptor agonists [ 8 ] It acts in the same way as incretins (hormones produced in the gut) by increasing ...
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