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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol has been marketed in the United States since 19 August 1966, when it was first approved by FDA under the trade name Zyloprim. [40] Allopurinol was marketed at the time by Burroughs Wellcome. Allopurinol is a generic drug sold under a variety of brand names, including Allohexal, Allosig, Milurit, Alloril, Progout, Ürikoliz, Zyloprim ...

  3. Clearance (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Clearance_(pharmacology)

    In these cases, clearance is almost synonymous with renal clearance or renal plasma clearance. Each substance has a specific clearance that depends on how the substance is handled by the nephron. Clearance is a function of 1) glomerular filtration , 2) secretion from the peritubular capillaries to the nephron , and 3) reabsorption from the ...

  4. Elimination (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Elimination_(pharmacology)

    Clearance is therefore expressed as the plasma volume totally free of the drug per unit of time, and it is measured in units of volume per units of time. Clearance can be determined on an overall, organism level («systemic clearance») or at an organ level (hepatic clearance, renal clearance etc.). The equation that describes this concept is:

  5. How to leverage cash prices and discount cards for ...

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    Explore multiple discount card options: Numerous websites and organizations offer free prescription discount cards. Try using several different cards to see which one provides the best price for ...

  6. CYP1A2 - Wikipedia

    en.wikipedia.org/wiki/CYP1A2

    Moderate inhibitor being one that causes at least a 2-fold increase in the plasma AUC values of sensitive substrates metabolized through CYP1A2, or 50-80% decrease in clearance thereof. [ 18 ] Weak inhibitor being one that causes at least a 1.25-fold but less than 2-fold increase in the plasma AUC values of sensitive substrates metabolized ...

  7. ‘Sinister’ romance scammer allegedly used dating apps to ...

    www.aol.com/news/sinister-romance-scammer...

    Aurora Phelps allegedly used online dating apps to lure at least four older men to meet her in person, then drugged them with sedatives and stole their money in a “sinister” romance scheme ...

  8. What happens if you go over your credit card limit? - AOL

    www.aol.com/finance/happens-over-credit-card...

    The average credit card balance in 2024 was $6,730, according to credit reporting agency Experian, which may put more consumers at risk of going over their credit limit at some point. We explore ...

  9. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

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