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Rates are falling fastest among women in their early 20s, the first generation to benefit from HPV vaccines, which were approved in 2006. HPV, the human papillomavirus, causes six types of cancer ...
The highest rates of HPV are in younger women, with a rate of 24% in women under 25 years. [183] Rates decline in older age groups in Europe and the Americas, but less so in Africa and Asia. The rates are highest in Sub-Saharan Africa (24%) and Eastern Europe (21%) and lowest in North America (5%) and Western Asia (2%).
HPV types 16 and 18 are the cause of 75% of cervical cancer cases globally, while 31 and 45 are the causes of another 10%. [45] Women who have multiple sexual partners, or have partners who have multiple sexual partners, regardless of sex are at higher risk of cervical cancer. [46] [47]
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 January 2025. Class of vaccines against human papillomavirus Pharmaceutical compound HPV vaccine Vaccine description Target Human papillomavirus (HPV) Vaccine type Protein subunit Clinical data Trade names Gardasil, others AHFS / Drugs.com Monograph MedlinePlus a615028 License data US DailyMed: Human ...
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The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
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Vaginal cancer is an extraordinarily rare form of cancer that develops in the tissue of the vagina. [1] Primary vaginal cancer originates from the vaginal tissue – most frequently squamous cell carcinoma, but primary vaginal adenocarcinoma, sarcoma, and melanoma have also been reported [2] – while secondary vaginal cancer involves the metastasis of a cancer that originated in a different ...
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