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Forensic biology is the application of biological principles and techniques in the investigation of criminal and civil cases. [1] [2]Forensic biology is primarily concerned with analyzing biological and serological evidence in order to obtain a DNA profile, which aids law enforcement in the identification of potential suspects or unidentified remains.
Developed in 1991, [10] DQ alpha testing was the first forensic DNA technique that utilized the polymerase chain reaction. [11] This technique allowed for the use of far fewer cells than RFLP analysis making it more useful for crime scenes that did not have the large amounts of DNA material that was previously required. [ 12 ]
Forensic science, also known as criminalistics, [1] is the application of science principles and methods to support legal decision-making in matters of criminal and civil law. During criminal investigation in particular, it is governed by the legal standards of admissible evidence and criminal procedure.
STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. [3] Scientific tools such as FBI approved STRmix incorporate this research technique.
In a paper published in the journal Forensic Science International: Genetics, the Israeli researchers demonstrated that it is possible to manufacture DNA in a laboratory, thus falsifying DNA evidence. The scientists fabricated saliva and blood samples, which originally contained DNA from a person other than the supposed donor of the blood and ...
Forensic DNA analysis can be a useful tool in aiding forensic identification because DNA is found in almost all cells of our bodies except mature red blood cells. Deoxyribonucleic acid is located in two different places of the cell, the nucleus ; which is inherited from both parents, and the mitochondria ; inherited maternally.
DNA phenotyping is the process of predicting an organism's phenotype using only genetic information collected from genotyping or DNA sequencing.This term, also known as molecular photofitting, is primarily used to refer to the prediction of a person's physical appearance and/or biogeographic ancestry for forensic purposes.
DNA methylation is a common epigenetic mark being studied as potential evidence in forensic science. [5] [6] Unlike DNA, realistic DNA methylation is less likely be planted at crime scenes.> [6] Current methods to fabricate DNA usually exclude important methylation marks found in biological tissues making this a way to confirm the identity of an individual when evidence is being assessed.
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