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Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the family of Matonaviridae, whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid.
The 1962–1965 rubella epidemic was an outbreak of rubella across Europe and the United States. [ 1 ] [ 2 ] The Rubella virus, also known as the German measles, is a single-stranded RNA virus from the family Togaviridae and genus Rubivirus . [ 3 ]
Rubella, also known as German measles or three-day measles, [6] is an infection caused by the rubella virus. [3] This disease is often mild, with half of people not realizing that they are infected. [ 1 ] [ 7 ] A rash may start around two weeks after exposure and last for three days. [ 1 ]
Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
The Rubella virus 3′ cis-acting element RNA family represents a cis-acting element found at the 3′ UTR in the rubella virus. This family contains three conserved step loop structures. [ 1 ] Calreticulin (CAL), which is known to bind calcium in most eukaryotic cells, is able to specifically bind to the first stem loop of this RNA. [ 1 ]
Rubella vaccine is a vaccine used to prevent rubella. [1] Effectiveness begins about two weeks after a single dose and around 95% of people become immune. Countries with high rates of immunization no longer see cases of rubella or congenital rubella syndrome. When there is a low level of childhood immunization in a population it is possible for ...
Many well known viruses are found in this group, including the picornaviruses (which is a family of viruses that includes well-known viruses like Hepatitis A virus, enteroviruses, rhinoviruses, poliovirus, and foot-and-mouth virus), SARS virus, hepatitis C virus, yellow fever virus, and rubella virus.
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