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The symptoms of pseudothrombophlebitis include pain, swelling, erythema and tenderness. It most commonly, but not exclusively, affects the legs. The presence of a popliteal cyst makes this diagnosis more likely. However, the presence of a popliteal cyst does not rule out deep vein thrombosis and warrants further investigation ...
Chronic venous insufficiency (CVI) is a medical condition characterized by blood pooling in the veins, leading to increased pressure and strain on the vein walls. [1] The most common cause of CVI is superficial venous reflux, which often results in the formation of varicose veins, a treatable condition. [2]
Of the vinca alkaloids, the most neurotoxic drug is vincristine. Vincristine disrupts the microtubular axonal transport system, which induces axonal neuropathy, distal numbness and tingling, and pain. [3] 4) Epothilones, mainly ixabepilone, are relatively new drugs that can be used to treat non-small lung, ovarian, and prostate cancers. [3]
The gastrocnemius muscle is prone to spasms, which are painful, involuntary contractions of the muscle that may last several minutes. [5] A severe ankle dorsiflexion force may result in a Medial Gastrocnemius Strain (MGS) injury of the muscle, commonly referred to as a "torn" or "strained" calf muscle, which is acutely painful and disabling. [6]
This valvular incompetence combined with persistent venous obstruction from thrombus increases the pressure in veins and capillaries. Venous hypertension induces a rupture of small superficial veins, subcutaneous hemorrhage [7] and an increase of tissue permeability. That is manifested by pain, swelling, discoloration, and even ulceration. [8]
[4] [5] Distal pulses are palpable early on but may diminish over time, and doppler signal can be usually heard throughout disease progression. [6] The left limb is more commonly affected due to its vascular anatomy (the right internal iliac artery directly overlies the left iliac vein).
Treatment and the potential outcome of the treatment may depend on the cause. Anything that creates pressure in the tarsal tunnel can cause TTS. This would include benign tumors or cysts, bone spurs, inflammation of the tendon sheath, nerve ganglions, or swelling from a broken or sprained ankle.
Superficial vein thrombosis (SVT) is a blood clot formed in a superficial vein, a vein near the surface of the body. Usually there is thrombophlebitis , which is an inflammatory reaction around a thrombosed vein, presenting as a painful induration (thickening of the skin) with redness .