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Sensitivity and specificity values alone may be highly misleading. The 'worst-case' sensitivity or specificity must be calculated in order to avoid reliance on experiments with few results. For example, a particular test may easily show 100% sensitivity if tested against the gold standard four times, but a single additional test against the ...
Sensitivity (physiology), the ability of an organism or organ to respond to external stimuli Sensory processing sensitivity, a personality trait in humans; Sensitivity and specificity, statistical measures of the performance of binary classification tests; Allergic sensitivity, the strength of a reaction to an allergen
The relationship between sensitivity and specificity, as well as the performance of the classifier, can be visualized and studied using the Receiver Operating Characteristic (ROC) curve. In theory, sensitivity and specificity are independent in the sense that it is possible to achieve 100% in both (such as in the red/blue ball example given above).
In a classification task, the precision for a class is the number of true positives (i.e. the number of items correctly labelled as belonging to the positive class) divided by the total number of elements labelled as belonging to the positive class (i.e. the sum of true positives and false positives, which are items incorrectly labelled as belonging to the class).
Biological specificity is the tendency of a characteristic such as a behavior or a biochemical variation to occur in a particular species. Biochemist Linus Pauling stated that "Biological specificity is the set of characteristics of living organisms or constituents of living organisms of being special or doing something special.
Photonic biosensors with ultra-sensitivity are nowadays being developed at a research level to easily detect cancerous cells within the patient's urine. [30] Different research projects aim to develop new portable devices that use cheap, environmentally friendly, disposable cartridges that require only simple handling with no need of further ...
In addition to their sensitivity and specificity, nanosensors offer significant advantages in cost and response times, making them suitable for high-throughput applications. Nanosensors provide real-time monitoring compared to traditional detection methods such as chromatography and spectroscopy.
TetR as a homodimer: Each monomer is shown in purple or salmon. The helix-turn-helix motif is shown in deep red. Tet Repressor proteins (otherwise known as TetR) are proteins playing an important role in conferring antibiotic resistance to large categories of bacterial species.