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Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about three people per million members of the population. [1] It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. [ 2 ]
“Margaritaville” singer Jimmy Buffet died of Merkel cell carcinoma on Sept. 1. Merkel cell carcinoma is a rare and aggressive form of skin cancer. Experts stress the importance of early detection.
Merkel cell carcinoma accounts for fewer than 1% of all skin cancers — but when it metastasizes it often turns deadly. What you need to know about the rare form of skin cancer that killed Jimmy ...
Rare and deadly type of skin cancer doesn't look like other types.
The reasons why 20% of Merkel cell carcinoma are negative for the virus remain completely unknown but speculations include the possibility that "Merkel cell carcinoma" is actually two or more closely related cancers, only one of which is infected with MCV. Misdiagnosis of this difficult cancer may also account for some of the negative results.
Retifanlimab, sold under the brand name Zynyz, is an anti-cancer medication used for the treatment of Merkel cell carcinoma. [1] Retifanlimab is a programmed death receptor-1 (PD-1)–blocking monoclonal antibody .
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Less common skin cancers include: Merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, porocarcinoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, keratoacanthoma, and skin sarcomas, such as angiosarcoma, dermatofibrosarcoma protuberans, Kaposi's sarcoma, leiomyosarcoma.