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  2. WHO Model List of Essential Medicines for Children - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children [1] or EMLc [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe in children up to twelve years of age to meet the most important needs in a health system.

  3. Endothelial dysfunction - Wikipedia

    en.wikipedia.org/wiki/Endothelial_dysfunction

    Endothelial dysfunction may be involved in the development of atherosclerosis [5] [6] [7] and may predate vascular pathology. [ 5 ] [ 8 ] Endothelial dysfunction may also lead to increased adherence of monocytes and macrophages , as well as promoting infiltration of low-density lipoprotein (LDL) in the vessel wall. [ 9 ]

  4. Flow-mediated dilation - Wikipedia

    en.wikipedia.org/wiki/Flow-mediated_dilation

    FMD is a noninvasive measure of blood vessel health (endothelial dysfunction [5] [6]) which (when low) is at least as predictive of cardiovascular disease as traditional risk factors. [4] [7] [8] Major cardiovascular disease associated with low FMD include cardiac death, myocardial infarction, and stroke. [8]

  5. Angina - Wikipedia

    en.wikipedia.org/wiki/Angina

    The primary cause of microvascular angina is unknown, but factors apparently involved are endothelial dysfunction and reduced flow (perhaps due to spasm) in the tiny "resistance" blood vessels of the heart. [18] Since microvascular angina is not characterized by major arterial blockages, it is harder to recognize and diagnose. [19] [20] [21]

  6. Chronic endothelial injury hypothesis - Wikipedia

    en.wikipedia.org/wiki/Chronic_endothelial_injury...

    The chronic endothelial injury hypothesis is one of two major mechanisms postulated to explain the underlying cause of atherosclerosis and coronary heart disease (CHD), the other being the lipid hypothesis. Although an ongoing debate involving connection between dietary lipids and CHD sometimes portrays the two hypotheses as being opposed, they ...

  7. Atherosclerosis - Wikipedia

    en.wikipedia.org/wiki/Atherosclerosis

    Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and driven by elevated levels of cholesterol in the blood. [9]

  8. Microvascular angina - Wikipedia

    en.wikipedia.org/wiki/Microvascular_angina

    The treatment consists of drugs, mainly to relieve chest pain, but a very important part of the treatment is regularly visiting the doctor and repeating the tests to make sure the condition was taken care of in full. The first step in managing Microvascular angina is the administration of nitrates which may relieve the chest pain. They are used ...

  9. Prostaglandin E1 - Wikipedia

    en.wikipedia.org/wiki/Prostaglandin_E1

    Prostaglandin E 1 (PGE 1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). [2] In infants with congenital heart defects, it is delivered by slow injection into a vein to open the ductus arteriosus until surgery can be carried out. [3]