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Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [5] [4] It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease, short bowel syndrome, [4] Crohn's disease, and ulcerative colitis. [5]
By binding to μ-opioid receptors, loperamide inhibits acetylcholine release and decreases excitation of neurons in the myenteric plexus, which leads to a decrease in peristalsis. [4] Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating ...
It contains loperamide and simethicone. Loperamide is a μ-opioid receptor agonist that works in the intestines. [1] Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal ...
Many counties in the Northeast have moderate to high numbers of doctors certified to treat buprenorphine patients. But just 31 percent of the 7,745 doctors in those areas are certified to treat the legal limit of 100 patients.
"The Philippines is not provoking conflict," Medel Aguilar told ... return to the right track of properly resolving differences through dialogue and consultation, and work with China to manage the ...
A day after the 2016 presidential election, presidential forerunner Duterte said, "I will be a dictator [...] but only against forces of evil – criminality, drugs and corruption in government", and vowed that if he failed to fulfill his promise to end crime, corruption, and drugs within the first six months of his term, he would step down from the presidency. [10]
A champion rower has died while free-diving. According to a GoFundMe page, shared last week, 27-year-old Austin Regier died in the Philippines on November 14, 2024. "He was swimming with new ...
MANILA (Reuters) -The Philippines did not consider invoking a mutual defence treaty with the United States after accusing China of disrupting a resupply mission in the disputed South China Sea ...