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Chimney sweeps' cancer, also called soot wart or scrotal cancer, is a squamous cell carcinoma of the scrotum. It has the distinction of being the first reported form of occupational cancer, and was initially identified by Percivall Pott in 1775. [1] It was initially noticed as being prevalent amongst chimney sweeps.
Percivall Pott, engraved from an original picture by Nathaniel Dance-Holland, National Library of Medicine, Images from the History of Medicine.. Percivall Pott (6 January 1714, in London – 22 December 1788) was an English surgeon, one of the founders of orthopaedics, and the first scientist to demonstrate that cancer may be caused by an environmental carcinogen, namely chimney sweeps ...
Studies conducted before smoking and lung cancer were scientifically related connected a higher rate of smoking to lung cancer incidence, and eventually mortality 20 years later. [2] In 1775, Percivall Pott’s discovery of the high incidence of scrotal cancer in chimney sweeps demonstrated that charred organic substances were carcinogenic.
Occupational cancer is cancer caused by occupational hazards. Several cancers have been directly tied to occupational hazards, including chimney sweeps' carcinoma , mesothelioma , and others. Types of hazards
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The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.
In the 18th century, young British chimney sweeps who climbed into chimneys suffered from chimney sweeps' carcinoma, a scrotal cancer peculiar to their profession, and this was connected to the effects of soot in 1775, [10] in the first work of occupational cancer epidemiology and also the first connection of any chemical mixture to cancer formation.
IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). [1] This category is used when there is sufficient evidence of carcinogenicity in humans.