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A gallstone is a stone formed within the gallbladder from precipitated bile components ... A high fat diet during weight loss also appears to prevent gallstones. [41 ...
However, VLCD may increase the risk of developing gallstones if the fat content of VLCD is not sufficient, but data is lacking to know the precise amount of fat that is necessary to avoid gallstones formation. [26] [27] Indeed, dietary fat stimulates gall bladder contraction, thus, if following a fat-free VLCD, the bladder does not empty. [26]
The first descriptions of gallstones appear to have been in the Renaissance, perhaps because of the low incidence of gallstones in earlier times owing to a diet with more cereals and vegetables and less meat. [37] Anthonius Benevinius in 1506 was the first to draw a connection between symptoms and the presence of gallstones. [37]
Deoxycholic acid (DCA) is increased in the colonic contents of humans in response to a high fat diet. [33] In populations with a high incidence of colorectal cancer, fecal concentrations of bile acids are higher, [34] [35] and this association suggests that increased colonic exposure to bile acids could play a role in the development of cancer.
A low-fat diet is one that restricts fat, and often saturated fat and cholesterol as well. Low-fat diets are intended to reduce the occurrence of conditions such as heart disease and obesity. For weight loss, they perform similarly to a low-carbohydrate diet , since macronutrient composition does not determine weight loss success. [ 1 ]
Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...
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This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturate the stones even more). [6] [7] Cholic acid and chenodeoxycholic acid are the most important human bile acids. Other species may synthesize different bile acids as their predominant primary bile ...
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