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Human betaherpesvirus 5, also called human cytomegalovirus (HCMV,HHV-5), [2] is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is also commonly called CMV. [3]
Cidofovir (CDV) does not require initial phosphorylation for its antiviral action. Further phosphorylation to the triphosphate form of GCV and CDV is performed by cellular kinases. The nucleoside-triphosphate-analogues compete with the cellular nucleotide triphosphates at the viral polymerase pUL54 and are incorporated into the viral DNA.
It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test. [1] Tzanck cells (acantholytic cells) are found in: Herpes simplex [2] Varicella and herpes zoster; Pemphigus vulgaris; Cytomegalovirus; Arnault Tzanck did the first cytological examinations in order to diagnose ...
In the past nucleic acid tests have mainly been used as a secondary test to confirm positive serological results. [3] However, as they become cheaper and more automated, they are increasingly becoming the primary tool for diagnostics and can also be use for monitoring of treatment of viral infected individuals t.
The 11 species in this genus include human betaherpesvirus 5 (HCMV, human cytomegalovirus, HHV-5), which is the species that infects humans. Diseases associated with HHV-5 include mononucleosis and pneumonia , [ 4 ] [ 5 ] and congenital CMV in infants can lead to deafness and ambulatory problems.
Human herpesvirus 6 (HHV-6) is the common collective name for human betaherpesvirus 6A (HHV-6A) and human betaherpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host.
Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
This phosphonic acid derivative (marketed by Clinigen as foscarnet sodium under the trade name Foscavir) is an antiviral medication used to treat herpes viruses, including drug-resistant cytomegalovirus (CMV) and herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2). It is particularly used to treat CMV retinitis