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For the treatment of simple cystitis in children, a five-day oral course of cephalexin is the preferred choice. As for children with suspected pyelonephritis, a ten-day treatment regimen is recommended. In such cases, a third-generation cephalosporin, such as cefdinir, is suggested as an appropriate option.
Lower urinary tract infections may involve the bladder (cystitis) or urethra while upper urinary tract infections affect the kidney (pyelonephritis). [10] Symptoms from a lower urinary tract infection include suprapubic pain, painful urination ( dysuria ), frequency and urgency of urination despite having an empty bladder. [ 1 ]
Even when caught early, aggressive treatment is required. [6] Antibiotics are proven to cure Emphysematous cystitis over time and reduce the amount of gas inside the bladder wall. Prognosis is poor if antibiotics are not used to treat the patient. Additional treatment consists of urinary drainage and good control of blood glucose.
Hemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria, hematuria, and hemorrhage. The disease can occur as a complication of cyclophosphamide , ifosfamide and radiation therapy.
Nitrofurantoin cannot be used to treat infections other than simple cystitis. At the concentrations achieved in urine (>100 μg/mL), nitrofurantoin is a bactericide . It is bacteriostatic against most susceptible organisms at concentrations less than 32 μg/mL.
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