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Methicillin-resistant Staphylococcus aureus (MRSA) is a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus. MRSA is responsible for several difficult-to-treat infections in humans. It caused more than 100,000 deaths worldwide attributable to antimicrobial resistance in 2019. MRSA is any ...
Staphylococcus scalded skin syndrome – Staphylococcus scalded skin syndrome is caused by toxins produced when a staph infection gets too severe. It is characterized by a fever, rash, and blisters. Methicillin-resistant Staphylococcus aureus (MRSA) – MRSA is one of the most common antibiotic-resistant strains of staph bacteria. It is more ...
Staphylococcus aureus (/ ˌ s t æ f ɪ l ə ˈ k ɒ k ə s ˈ ɔːr i ə s,-l oʊ-/, [16] [17] Greek σταφυλόκοκκος ' grape-cluster berry ', Latin aureus, ' golden ') is a facultative anaerobic, gram-positive coccal (round) bacterium also known as "golden staph" and "oro staphira".
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
Staphylococcus species are facultative anaerobes (capable of growth both aerobically and anaerobically). [15] All species grow in the presence of bile salts. All species of Staphylococcus aureus were once thought to be coagulase-positive, but this has since been disproven. [16] [17] [18] Growth can also occur in a 6.5% NaCl solution. [15]
A carbuncle is a cluster of boils caused by bacterial infection, most commonly with Staphylococcus aureus or Streptococcus pyogenes. [1] The presence of a carbuncle is a sign that the immune system is active and fighting the infection. [2]
[5] [4] MRSA empiric therapy is also not warranted unless the patient has a critical infection such as sepsis, if the rate of MRSA infections are particularly high in a local area, or if the patient had a previous MRSA infection. [5] The duration of antibiotics depends on the severity of infection, ranging anywhere from 1–12 weeks.
Importantly, S. aureus is generally coagulase-positive, meaning that a positive coagulase test would indicate the presence of S. aureus or any of the other 11 coagulase-positive Staphylococci. [1] A negative coagulase test would instead show the presence of coagulase-negative organisms such as S. epidermidis or S. saprophyticus.