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Year of discovery Name of the drug Year when the synthesis mechanism was developed Year that was Patented Governmental approval Patented expiry Drug type * 2000: Bevacizumab: 2004: 2024 MA 2001: Valdecoxib: 2016: N/A SM 2001: Etoricoxib: 2016: N/A SM 2003: Alirocumab: 2015: 2035 MA 2006: Linagliptin: 2011 [31] 2031 SM 2007: Apixaban: 2012: 2032 ...
Abelardo Aguilar (November 3, 1917 – September 22, 1993) was a Filipino doctor from Iloilo, Philippines who worked as a medical representative for Eli Lilly and Company. [ 1 ] [ 2 ] Discovery of erythromycin
Then in 1949, he submitted samples of his work to the company's research team who in 1952 declared the discovery of a new kind of antibiotic. According to the team, the new drug was capable of treating several kinds of infections minus the common side-effects of antibiotics, and could be given to those who were allergic to penicillin. [59]
In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. [ 1 ] Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin .
[8] [10] fl. 425 BC – Diogenes of Apollonia [8] c. 484 – 425 BC – Herodotus tells us Egyptian doctors were specialists: Medicine is practiced among them on a plan of separation; each physician treats a single disorder, and no more. Thus the country swarms with medical practitioners, some undertaking to cure diseases of the eye, others of ...
Forward (classical) and reverse pharmacology approaches in drug discovery. In the field of drug discovery, classical pharmacology, [1] also known as forward pharmacology, [2] [3] [4] or phenotypic drug discovery (PDD), [5] relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify ...
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The following dates are approximations. 700 BC: Pythagoras's theorem is discovered by Baudhayana in the Hindu Shulba Sutras in Upanishadic India. [18] However, Indian mathematics, especially North Indian mathematics, generally did not have a tradition of communicating proofs, and it is not fully certain that Baudhayana or Apastamba knew of a proof.