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Genetic testing, also known as DNA ... about the fetus early in pregnancy. [12] ... is an important consideration in making decisions about a pregnancy. Prior to the ...
Disease testing: Whether the sex of the fetus is male or female allows the determination of the risk of a particular X-linked recessive genetic disorder in a particular pregnancy, especially where the mother is a genetic carrier of the disorder. [41] Preparation, for any sex-dependent aspects of parenting. [citation needed]
The ACOG recommends genetic screening before pregnancy to all pregnant women planning to have a family. [61] After comprehensive counseling and discussion that acknowledges residual risks, it is important to respect the patients' right of choosing whether or not to pursue any component of genetic testing. [citation needed]
The pregnancy loss rate in pregnancies with confined placental mosaicism, diagnosed by chorionic villus sampling, is higher than among pregnancies without placental mosaicism. It may be that sometimes the presence of significant numbers of abnormal cells in the placenta interferes with proper placental function.
Transabdominal chorionic villus sampling is an alternative to amniocentesis if genetic diagnostic testing is to be performed in the first trimester between ten and 15 weeks' gestation. [3] It is important to note that prenatal genetic testing cannot identify all possible fetal genetic abnormalities or their outcomes. [5]
It entails sampling of the chorionic villus (placental tissue) and testing it for chromosomal abnormalities, usually with FISH or PCR. CVS usually takes place at 10–12 weeks' gestation, earlier than amniocentesis or percutaneous umbilical cord blood sampling. It is the preferred technique before 15 weeks. [2]
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