Search results
Results from the WOW.Com Content Network
The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryotic cell, and has many other important functions such as protein folding.It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER).
The rough endoplasmic reticulum is so named because the cytoplasmic surface is covered with ribosomes, giving it a bumpy appearance when viewed through an electron microscope. The smooth ER appears smooth since its cytoplasmic surface lacks ribosomes. [27]
Synthesis of proteins is by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. [citation needed] The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes.
Rough (containing ribosomes) and smooth (without ribosomes) microsomes are made from the endoplasmic reticulum through cell disruption. These microsomes have an inside that is exactly the same as the endoplasmic reticulum lumen. Both forms of microsomes can be purified by a process known as equilibrium density centrifugation. Rough and smooth ...
The acidophilic cytoplasm usually contains numerous membrane-bound lipid droplets and large amounts of smooth endoplasmic reticulum (SER). [4] Besides the abundance of SER with scattered patches of rough endoplasmic reticulum , several mitochondria are also prominent within the cytoplasm .
Conversely, the SER is devoid of ribosomes and tends to be more tubular in structure. The peripheral ER is dynamic: the tubules continuously form and disappear and the sheets rearrange. [ 4 ] ER shaping proteins (reticulons and Dp1/Yop1p) play key roles in generating and maintaining this unique reticular morphology of the ER.
[3] [4] MCS are important in the function of the endoplasmic reticulum (ER), [5] since this is the major site of lipid synthesis within cells. [6] The ER makes close contact with many organelles, including mitochondria, Golgi, endosomes, lysosomes, peroxisomes, chloroplasts and the plasma membrane. [7]
The spine apparatus (SA) is a specialized form of endoplasmic reticulum (ER) that is found in a subpopulation of dendritic spines in central neurons.It was discovered by Edward George Gray in 1959 when he applied electron microscopy to fixed cortical tissue. [1]