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Ginkgo biloba leaves and sarcotesta contain ginkgolic acids [82] – which are highly allergenic – long-chain alkylphenols, such as bilobol or adipostatin A [83] (bilobol is a substance related to anacardic acid from cashew nut shells and urushiols present in poison ivy and other Toxicodendron spp.) [9] [79] Individuals with a history of ...
Bilobalide is important for producing several of the effects of Ginkgo biloba extracts, and it has neuroprotective effects, [3] [4] as well as inducing the liver enzymes CYP3A1 and CYP1A2, [5] which may be partially responsible for interactions between ginkgo and other herbal medicines or pharmaceutical drugs.
Complexation with phospholipids has been applied to a number of popular herbal extracts and active molecules including Ginkgo biloba extract, [4] bilobalide isolated from Ginkgo biloba, [5] silybin isolated from milk thistle (Silybum marianum), [6] curcumin isolated from turmeric, [7] and green tea extract (Camellia sinensis). [8]
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For instance, in Japan and China, Ginkgo biloba is used to treat cough, bronchial asthma, irritable bladder and alcohol use disorder. [6] Ginkgotoxin is found in the seeds and, in lesser amounts, in the leaves of Ginkgo biloba. The seeds can be consumed as is and the leaves can be used to prepare the dietary supplements.
Add lemonade to a large mug and microwave for 30 to 60 seconds until just warmed. Add 6 ounces of hot water (just off the boil) to the mug and steep one teapigs green tea with peach for 5 minutes.
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Ginkgolide B, specifically, is a diterpenoid trilactone with six five-membered rings. It contains a spiro[4,4]-nonane carbocyclic ring, a tetrahydrofuran ring, and a very specific tert-butyl group at one of the rings (Figure 1).
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