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The diagram emphasizes events that cross the system boundary from actors to systems. A system sequence diagram should be done for the main success scenario of the use case, and frequent or complex alternative scenarios. There are two kinds of sequence diagrams: Sequence Diagram (SD): A regular version of sequence diagram describes how the ...
Action sequence-Action state-Action steps-Activation - the time during which an object has a method executing. It is often indicated by a thin box or bar superimposed on the Object's lifeline in a Sequence Diagram; Activity diagram - a diagram that describes procedural logic, business process or work flow. An activity diagram contains a number ...
A diagram is a partial graphic representation of a system's model. The set of diagrams need not completely cover the model and deleting a diagram does not change the model. The model may also contain documentation that drives the model elements and diagrams (such as written use cases). UML diagrams represent two different views of a system ...
A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA. [1] In bottom-up sequencing projects, a contig refers to overlapping sequence data (); [2] in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that is used to guide sequencing and assembly. [3]
Alternative Lengthening of Telomeres (also known as "ALT") is a telomerase-independent mechanism by which cancer cells avoid the degradation of telomeres.. At each end of the chromosomes of most eukaryotic cells, there is a telomere: a region of repetitive nucleotide sequences which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.
One method is the Terminal Restriction Fragment (TRF) southern blot. [ 49 ] [ 50 ] There is a Web-based Analyser of the Length of Telomeres ( WALTER ), software processing the TRF pictures. [ 51 ] A Real-Time PCR assay for telomere length involves determining the Telomere-to-Single Copy Gene (T/S) ratio, which is demonstrated to be proportional ...
Amplified fragment length polymorphism (AFLP-PCR or AFLP) is a PCR-based tool used in genetics research, DNA fingerprinting, and in the practice of genetic engineering. Developed in the early 1990s by Pieter Vos, [ 1 ] AFLP uses restriction enzymes to digest genomic DNA , followed by ligation of adaptors to the sticky ends of the restriction ...
In bioinformatics, sequence assembly refers to aligning and merging fragments from a longer DNA sequence in order to reconstruct the original sequence. [1] This is needed as DNA sequencing technology might not be able to 'read' whole genomes in one go, but rather reads small pieces of between 20 and 30,000 bases, depending on the technology used. [1]