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D LCO or T LCO (diffusing capacity or transfer factor of the lung for carbon monoxide (CO), [1]) is the extent to which oxygen passes from the air sacs of the lungs into the blood. Commonly, it refers to the test used to determine this parameter. It was introduced in 1909. [2]
Spirometry (meaning the measuring of breath) is the most common of the pulmonary function tests (PFTs). It measures lung function, specifically the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled.
Repeatability of the PFT is determined by comparing the values of forced vital capacity (FVC) and forced expiratory volume at 1 second (FEV1). The difference between the highest values of two FVCs need to be within 5% or 150 mL. When the FVC is less than 1.0 L, the difference between the highest two values must be within 100 mL.
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The Annals of the American Thoracic Society is a peer-reviewed medical journal that publishes clinical trials and original scientific research related to adult and pediatric pulmonary and respiratory sleep medicine, as well as adult critical care medicine, that is applicable to clinical practice, the formative and continuing education of clinical specialists, and the advancement of public health.
In 1960, the European Community for Coal and Steel (ECCS) first recommended guidelines for spirometry. [7] The organization then published predicted values for parameters such as spirometric indices, residual volume, total lung capacity, and functional residual capacity in 1971. [ 8 ]
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