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Pain in cancer can be produced by mechanical (e.g. pinching) or chemical (e.g. inflammation) stimulation of specialized pain-signalling nerve endings found in most parts of the body (called nociceptive pain), or it may be caused by diseased, damaged or compressed nerves, in which case it is called neuropathic pain.
Pressure on the kidney or ureter from a tumor outside the kidney can cause extreme flank pain. [7] Local recurrence of cancer after the removal of a kidney can cause pain in the lumbar back, or L1 or L2 spinal nerve pain in the groin or upper thigh, accompanied by weakness and numbness of the iliopsoas muscle, exacerbated by activity. [4]
Many patients first complain of pain that may be worse at night, may be intermittent and of varying intensity and may have been occurring for a long time. Teenagers who are active in sports often complain of pain in the lower femur, or immediately below the knee. If the tumor is large, it can present as overt localised swelling.
It mostly affects people over the age of 65, with symptoms including persistent bone pain, particularly in the spine, hips and chest, as well as tiredness, shortness of breath, repeated infections ...
Doctors said bump on woman's knee was harmless. It was stage 3 sarcoma. She participated in a Stand Up 2 Cancer clinical trial and is cancer free.
It may also be caused by therapies such as radiation or chemotherapy. With competent management, cancer pain can be eliminated or well controlled in 80% to 90% of cases, but nearly 50% of cancer patients in the developed world receive less than optimal care. Worldwide, nearly 80% of people with cancer receive little or no pain medication. [15]
Dr. Narayanan says that bone pain can also be a sign of prostate cancer recurrence in patients who have already had the disease. The link between prostate cancer and bone pain may be a surprising one.
Another commonly used method for treating bone pain is radiotherapy, which can be safely administered in low doses. Radiotherapy utilizes radioactive isotopes and other atomic particles to damage the DNA in cells, thus leading to cell death. By targeting cancer tumors, radiotherapy can lead to decrease in tumor size and even tumor destruction. [18]
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