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Other studies have also shown that this condition may affect women more than men, as women may experience swelling due to fluid retention in the legs, feet or abdomen after being stationary. [4] The proposed mechanism includes the possibility that increased leg fat may impair the ability to dissipate heat. [ 4 ]
While nicotinic acid (niacin) may be used for this purpose, nicotinamide has the benefit of not causing skin flushing. [4] As a cream, it is used to treat acne, and has been observed in clinical studies to improve the appearance of aging skin by reducing hyperpigmentation and redness. [5] [6] It is a water-soluble vitamin. Side effects are minimal.
Niacin has been linked to a higher risk of heart disease. It is often added to flour and fortified cereals in the U.S. The B vitamin used to be a popular medication to lower high cholesterol.
The resulting name niacin was derived from nicotinic acid + vitamin. [94] [66] Carpenter found in 1951, that niacin in corn is biologically unavailable, and can be released only in very alkaline lime water of pH 11. This explains why a Latin-American culture that used alkali-treated cornmeal to make tortilla was not at risk for niacin ...
According to a study, most of the people who experience pruritus daily have increased itching sensations and other associated symptoms during the night. Most studies reveal that senile pruritus is more common in men than women. [3] Common symptoms of senile pruritus include: [3] pain; heat sensation; cold sensation; bumps, blisters or spots ...
The US Recommended Dietary Allowance for niacin for adult women is 14 mg/day and for adult men 16 mg/day. Niacin is available as a prescription product, either immediate release (500 mg tablets; prescribed up to 3,000 mg/day) or extended release (500 and 1,000 mg tablets; prescribed up to 2,000 mg/day).
Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]
Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash. [1] In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. [1]
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