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Nevus depigmentosus is a loss of pigment in the skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to growth of the body.
Hypopigmentation can be caused by hereditary conditions such as vitiligo, melasma, pityriasis versicolor, pityriasis alba, albinism, and fungal infections. [ 4 ] Hyperpigmentation results from an increase in melanin synthesis, which is mostly brought on by sun exposure, dermatological disorders, hormones, aging, genetic factors, skin injuries ...
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
The restoration of pigment may be aided by topical application of 0.1% 8-methoxypsoralen, 0.5–1% coal tar, or anthralin, followed by sun exposure. [9] With good outcomes, different topical photochemotherapy regimens (topical psoralen UVA; PUVA) have been utilized to treat postinflammatory hypopigmentation brought on by a variety of illnesses. [2]
The convalescent phase is characterized by gradual tissue depigmentation of skin with vitiligo and poliosis, sometimes with nummular depigmented scars, as well as alopecia and diffuse fundus depigmentation resulting in a classic orange-red discoloration ("sunset glow fundus" [5] [8] [7]) and retinal pigment epithelium clumping and/or migration.
Vitiligo: Topical steroids, including calcineurin inhibitors. Patients can also have transplants if they are stable or a depigmentation with topical MBEH if the patient has widespread discoloration. Chemical or drug induced leukoderma: Avoidance of causative agent with subsequent treatment similar to vitiligo. Piebaldism: None; occasionally ...
Poliosis is present in half of patients with segmental vitiligo. [ 5 ] Vogt-Koyanagi-Harada Syndrome (VKH): VKH is a systemic autoimmune disorder affecting melanin-containing tissues, leading to uveitis , meningitis , and poliosis, which often involves the eyebrows and eyelashes.
The first World Vitiligo Day (also defined as “Vitiligo Awareness Day” or “Vitiligo Purple Fun day”, from the color chosen as Vitiligo Awareness Color [2]) was observed on June 25, 2011. The choice of June 25 as World Vitiligo Day is a memorial to musical artist Michael Jackson , who suffered from vitiligo from the early 1980s until his ...