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Spinal cord compression is commonly found in patients with metastatic malignancy. [10] Back pain is a primary symptom of spinal cord compression in patients with known malignancy. [11] Back pain may prompt a bone scan to confirm or exclude spinal metastasis. Rapid identification and intervention of metastatic spinal cord compression is ...
[11] [1] In some cases, symptoms may include double vision, numb chin, [6] back pain, leg weakness, sphincter-related problems, hydrocephalus, [12] loss of urine control, and difficulty walking. Other symptoms that are less common cranial nerve abnormalities, spinal symptoms such as limb weakness and paresthesia, and bowel and bladder dysfunction.
Metastasis occurs in about 39% of patients, most commonly to the lung. Features associated with poor prognosis include a large primary tumor (over 5 cm across), high grade disease, co-existent neurofibromatosis, and the presence of metastases. [5] It is a rare tumor type, with a relatively poor prognosis in children. [6]
Spinal nerve sheath tumors generally arise as single lesions. [1] Presence of multiple lesions is associated with genetic conditions including neurofibromatosis type 1, neurofibromatosis type 2, and Schwannomatosis. [1] [3] [4] Most spinal schwannomas are intradural-extramedullary, growing inside the thecal sac, but outside the spinal cord ...
Spinal cord compression is a form of myelopathy ... Symptoms suggestive of cord ... The median survival of patients with metastatic spinal cord compression is about ...
The base of the skull may be affected by metastases from cancer of the bronchus, breast or prostate, or cancer may spread directly to this area from the nasopharynx , and this may cause headache, facial paresthesia, dysesthesia or pain, or cranial nerve dysfunction – the exact symptoms depend on the cranial nerves impacted.
Brain metastasis: neurological symptoms such as headaches, [10] seizures, [10] and vertigo [10] Although advanced cancer may cause pain, it is often not the first symptom. Some patients, however, do not show any symptoms. [10] When the organ gets a metastatic disease it begins to shrink until its lymph nodes burst, or undergo lysis.
Metastasis occurrence indicates stage 4 cancer progression and carries a poor prognosis. [7] Cancer usually causes numerous and varying symptoms at this stage depending on the underlying cancer and metastasis location. [7] Importantly for diagnosis, a symptomatic primary lesion is localised through either surgery or radiation. [7]
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