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Oligohydramnios is a medical condition in pregnancy characterized by a deficiency of amniotic fluid, the fluid that surrounds the fetus in the abdomen, in the amniotic sac. The limiting case is anhydramnios , where there is a complete absence of amniotic fluid.
Post-maturity is more likely to happen when a mother has had a post-term pregnancy before. After one post-term pregnancy, the risk of a second post-term birth increases by 2 to 3 times. [8] Other, minor risk factors include an older or obese mother, a white mother, male baby, or a family history of post-maturity. [9]
Non-modifiable risk factors include a family history of diabetes, advanced maternal age, and ethnicity. Modifiable risk factors include maternal obesity. [ 14 ] There is an elevated demand for insulin during pregnancy which leads to increased insulin production from pancreatic beta cells .
Women with abnormal amounts of amniotic fluid, whether too much (polyhydramnios) or too little (oligohydramnios), are also at risk. [35] Anxiety and depression have been linked as risk factors for preterm birth. [35] [61] The use of tobacco, cocaine, and excessive alcohol during pregnancy increases the chance of preterm delivery.
Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
Risk factors include folate deficiency, drinking alcohol or smoking during pregnancy, poorly controlled diabetes, and a mother over the age of 35 years old. [5] [6] Many birth defects are believed to involve multiple factors. [6] Birth defects may be visible at birth or diagnosed by screening tests. [10]
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
Other risk factors include a multiple pregnancy, more than one previous delivery, and too much amniotic fluid. [ 2 ] [ 3 ] Whether medical rupture of the amniotic sac is a risk is controversial. [ 2 ] [ 3 ] The diagnosis should be suspected if there is a sudden decrease in the baby's heart rate during labor.