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Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
In biology and medicine, nitric oxide is however an important signalling molecule in nature and this fact is the basis of the most important applications of metal nitrosyls. The nitroprusside anion, [Fe(CN) 5 NO] 2− , a mixed nitrosyl cyano complex, has pharmaceutical applications as a slow release agent for NO.
The oligodynamic effect was discovered in 1893 as a toxic effect of metal ions on living cells, algae, molds, spores, fungi, viruses, prokaryotic, and eukaryotic microorganisms, even in relatively low concentrations. [7] This antimicrobial effect is shown by ions of copper as well as mercury, silver, iron, lead, zinc, bismuth, gold, and aluminium.
The Ministry of Health has warned that nitrous oxide is a prescription medicine whose sale or possession without a prescription is an offense under the Medicines Act. [136] This would seemingly prohibit all non-medicinal uses of nitrous oxide, although it is implied that only recreational use will be targeted.
The terminal oxide centers of polyoxometalate framework can in certain cases be replaced with other ligands, such as S 2−, Br −, and NR 2−. [5] [28] Sulfur-substituted POMs are called polyoxothiometalates. Other ligands replacing the oxide ions have also been demonstrated, such as nitrosyl and alkoxy groups. [23] [29]
The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. [ 2 ] [ 3 ] [ 4 ] Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections.
Iron oxide nanoparticles may also be used in magnetic hyperthermia as a cancer treatment method. In this method, the ferrofluid which contains iron oxide is injected to the tumor and then heated up by an alternating high frequency magnetic field. The temperature distribution produced by this heat generation may help to destroy cancerous cells ...
The oligodynamic effect (from Greek oligos, "few", and dynamis, "force") is a biocidal effect of metals, especially heavy metals, that occurs even in low concentrations. This effect is attributed to the antibacterial behavior of metal ions, which are absorbed by bacteria upon contact and damage their cell membranes .