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A muscle cell, also known as a myocyte, is a mature contractile cell in the muscle of an animal. [1] In humans and other vertebrates there are three types: skeletal, smooth, and cardiac (cardiomyocytes). [2] A skeletal muscle cell is long and threadlike with many nuclei and is called a muscle fiber. [3]
Many nuclei are needed by the skeletal muscle cell for the large amounts of proteins and enzymes needed to be produced for the cell's normal functioning. A single muscle fiber can contain from hundreds to thousands of nuclei. [25] A muscle fiber for example in the human biceps with a length of 10 cm can have as many as 3,000 nuclei. [25]
The fibres of striated muscle have a cylindrical shape with blunt ends, whereas those in smooth muscle are spindle-like with tapered ends. Striated muscle tissue has more mitochondria than smooth muscle. Both smooth muscle cells and cardiac muscle cells have a single nucleus, and skeletal muscle cells have many nuclei. [6]
A myofibril (also known as a muscle fibril or sarcostyle) [1] is a basic rod-like organelle of a muscle cell. [2] Skeletal muscles are composed of long, tubular cells known as muscle fibers, and these cells contain many chains of myofibrils. [3] Each myofibril has a diameter of 1–2 micrometres. [3]
Striated skeletal muscle cells in microscopic view. Skeletal muscle is broadly classified into two fiber types: type I (slow-twitch) and type II (fast-twitch). Type I, slow-twitch, slow oxidative, or red muscle is dense with capillaries and is rich in mitochondria and myoglobin, giving the muscle tissue its characteristic red color.
Cardiac and skeletal muscle cells contain structures called transverse tubules (T-tubules), which are extensions of the cell membrane that travel into the centre of the cell. T-tubules are closely associated with a specific region of the SR, known as the terminal cisternae in skeletal muscle, with a distance of roughly 12 nanometers, separating ...
Structure of a skeletal muscle. A key component in lateral force transmission in skeletal muscle is the extracellular matrix (ECM). Skeletal muscle is a complex biological material that is composed of muscle fibers and an ECM consisting of the epimysium, perimysium, and endomysium. It can be described as a collagen fiber-reinforced composite.
The protein complex composed of actin and myosin, contractile proteins, is sometimes referred to as actomyosin.In striated skeletal and cardiac muscle, the actin and myosin filaments each have a specific and constant length in the order of a few micrometers, far less than the length of the elongated muscle cell (up to several centimeters in some skeletal muscle cells). [5]
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