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The brain parenchyma refers to the functional tissue in the brain that is made up of the two types of brain cell, neurons and glial cells. [7] It is also known to contain collagen proteins. [8] Damage or trauma to the brain parenchyma often results in a loss of cognitive ability or even death.
The pathway consists of a para-arterial influx mechanism for CSF driven primarily by arterial pulsation, [2] which "massages" the low-pressure CSF into the denser brain parenchyma, and the CSF flow is regulated during sleep by changes in parenchyma resistance due to expansion and contraction of the extracellular space.
These form the ventricular system of the brain: [8] The neural stem cells of the developing brain, principally radial glial cells, line the developing ventricular system in a transient zone called the ventricular zone. [9] The prosencephalon divides into the telencephalon, which forms the cortex of the developed brain, and the diencephalon.
The glia limitans, or the glial limiting membrane, is a thin barrier of astrocyte foot processes associated with the parenchymal basal lamina surrounding the brain and spinal cord. It is the outermost layer of neural tissue , and among its responsibilities is the prevention of the over-migration of neurons and neuroglia , the supporting cells ...
In peripheral organs, lymphatic vessels are responsible for conducting lymph between different parts of the body. In general, lymphatic drainage is important for maintaining fluid homeostasis as well as providing a means for immune cells to traffic into draining lymph nodes from other parts of the body, allowing for immune surveillance of bodily tissues.
This is critical because the brain lacks a true lymphatic system. In the remainder of the body, small amounts of protein are able to leak from the parenchymal capillaries through the lymphatic system. In the brain, this ends up in the interstitial space. The protein portions are able to leave through the very permeable pia mater and enter the ...
From a paper by Oscar Arias-Carrión, 2008 In an embryonic rat brain, GAD67-binding marker tends to concentrate in subventricular zone. An image from Popp et al., 2009. [1] The subventricular zone (SVZ) is a region situated on the outside wall of each lateral ventricle of the vertebrate brain. [2] It is present in both the embryonic and adult ...
Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.