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The clinical signs and symptoms of leukostasis are non-specific but should be suspected in susceptible individuals with leukemia, a high white blood cell count (e.g., over 100,000), and new-onset neurologic or respiratory signs or symptoms. Rales may be heard when listening to the lungs with a stethoscope. [6]
Common symptoms present in the different types of leprosy include a runny nose; dry scalp; eye problems; skin lesions; muscle weakness; reddish skin; smooth, shiny, diffuse thickening of facial skin, ear, and hand; loss of sensation in fingers and toes; thickening of peripheral nerves; a flat nose from the destruction of nasal cartilages; and changes in phonation and other aspects of speech ...
Although the condition can affect people of all ages, it is commonly diagnosed in adults over age 60. [7] [3] The dominant signs and symptoms of the disease are: Generalized erythroderma – redness of the skin [3] Lymphadenopathy – swollen, enlarged lymph nodes [3]
Symptoms that may develop from damage to these organs include double vision , clouding of lenses of eyes, swelling of the optic disc (papilledema), partial loss of vision, shortness of breath, chest pain, epilepsy, and thickening of pericardium. [3] [4] Someone with the benign form may suddenly develop symptoms of the malignant form. [1]
Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. [1] The incidence of hairy cell leukemia (HCL) is 0.28-0.30 cases per 100,000 people in Europe and the United States and the prevalence is 3 cases per 100,000 in Europe with a lower prevalence in Asia, Africa and the Middle East.
The Kasukawa criteria require a minimum of one of the common symptoms, a positive anti-RNP antibody, as well as one or more symptoms of the mixed symptoms in at least two of the three disease categories to qualify for a diagnosis of MCTD. [69] It has a sensitivity of 75% [70] and a specificity of 99.8%. [32] Common symptoms: [69] Raynaud's ...
Up to 8% of men over 70 [6] Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white/gray lesion that cannot be considered as any other definable lesion."
Pyuria is the condition of urine containing white blood cells or pus.Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection.