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Ganglioneuroma (occasionally called a "ganglioma") is a rare and benign tumor of the autonomic nerve fibers arising from neural crest sympathogonia (undifferentiated cells of the sympathetic nervous system). [1] However, ganglioneuromas themselves are fully differentiated neuronal tumors that do not contain immature elements. [2]
Nodular ganglioneuroblastoma can be divided by prognosis. [2] ... Ganglioneuroma (benign) Ganglioneuroblastoma (intermediate). Neuroblastoma (aggressive) See also.
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A neuroma (/ nj ʊəˈr oʊ m ə /; plural: neuromata or neuromas) is a growth or tumor of nerve tissue. [1] Neuromas tend to be benign (i.e. not cancerous); many nerve tumors, including those that are commonly malignant, are nowadays referred to by other terms.
Diagnosis is typically based on examination. The ability to shine through the bump or any past decrease in size supports the diagnosis of the bump as a ganglion cyst. [4] Ganglion cysts are usually obvious upon observation. Medical imaging may be considered on infrequent occasions to rule out another diagnosis. [3] [4] Treatment is not necessary.
Histologically, ganglioglioma is composed of both neoplastic glial and ganglion cells which are disorganized, variably cellular, and non-infiltrative. Occasionally, it may be challenging to differentiate ganglion cell tumors from an infiltrating glioma with entrapped neurons.
When molecular diagnostics are not complete enough to allow precise classification, diagnosis should be designated by appending not otherwise specified (NOS). In case of a full molecular workup which does not match any of the standard WHO diagnosis, tumors are to be labeled not elsewhere classified (NEC).
A nervous system tumor is a tumor that arises within the nervous system, either the central nervous system (CNS) or the peripheral nervous system (PNS). [1] [2] Nervous system primary tumors include various types of brain tumor and spinal tumors, such as gliomas, and meningiomas (of the CNS), and schwannomas (of the PNS) and can be either benign or malignant.